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Reliable Single Cell Array CGH for Clinical Samples

21 Jan 2014

Abstract excerpt

BACKGROUND: Disseminated cancer cells (DCCs) and circulating tumor cells (CTCs) are extremely rare, but comprise the precursors cells of distant metastases or therapy resistant cells. The detailed molecular analysis of these cells may help to identify key events of cancer cell dissemination, metastatic colony formation and systemic therapy escape. METHODOLOGY/PRINCIPAL FINDINGS: Using the Ampli1™ whole genome...

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PMID: 24465780
DOI: 10.1371/journal.pone.0085907

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