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Article

Overview on Clinical Relevance of Intra-Tumor Heterogeneity

6 Apr 2018

Abstract excerpt

Today, clinical evaluation of tumor heterogeneity is an emergent issue to improve clinical oncology. In particular, intra-tumor heterogeneity (ITH) is closely related to cancer progression, resistance to therapy, and recurrences. It is interconnected with complex molecular mechanisms including spatial and temporal phenomena, which are often peculiar for every single patient. This review tries to describe all the...

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PMID: 29682505
DOI: 10.3389/fmed.2018.00085

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