Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts.

Molecular & cellular proteomics : MCP - 1 Apr 2015

Ramond Elodie, Gesbert Gael, Guerrera Ida Chiara, Chhuon Cerina, Dupuis Marion, Rigard Mélanie, Henry Thomas, Barel Monique, Charbit Alain

Abstract excerpt

Upon entry into mammalian host cells, the pathogenic bacterium Francisella must import host cell arginine to multiply actively in the host cytoplasm. We identified and functionally characterized an arginine transporter (hereafter designated ArgP) whose inactivation considerably delayed bacterial phagosomal escape and intracellular multiplication. Intramacrophagic growth of the ΔargP mutant was fully restored upon...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Bacterial Vaccines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytosol

Share to Microbial Viability

Share to Phagosomes

Share to Proteome

Share to Ribosomal Proteins

Share to Subcellular Fractions

Source

Open in PubMed Open full text

Identifiers

PMID: 25616868
DOI: 10.1074/mcp.M114.044552
PMCID: PMC4390266

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Importance of host cell arginine uptake in Francisella phagosomal escape and ribosomal protein amounts.PMID 25616868Read ↗

A Francisella tularensis pathogenicity island protein essential for bacterial proliferation within the host cell cytosol.Semantic proximity Read ↗

Cell biology and molecular ecology of<i>Francisella tularensis</i>Semantic proximity Read ↗

The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm.Semantic proximity Read ↗

Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway.Semantic proximity Read ↗

Glutamate utilization couples oxidative stress defense and the tricarboxylic acid cycle in Francisella phagosomal escape.Semantic proximity Read ↗

Uncovering the components of the Francisella tularensis virulence stealth strategy.Semantic proximity Read ↗

The arginine/ornithine binding protein ArgT plays an essential role in Brucella neotomae / Brucella melitensis to prevent intracellular killing and contribute to chronic persistence in the hostSemantic proximity Read ↗

Subversion of Host Recognition and Defense Systems by Francisella sppSemantic proximity Read ↗

Exploitation of Host Cell Biology and Evasion of Immunity by Francisella TularensisSemantic proximity Read ↗

EmrA1 membrane fusion protein of Francisella tularensis LVS is required for resistance to oxidative stress, intramacrophage survival and virulence in mice.Semantic proximity Read ↗

IglG and IglI of the Francisella Pathogenicity Island Are Important Virulence Determinants of Francisella tularensis LVSSemantic proximity Read ↗

Modulation of biogenesis of the Francisella tularensis subsp. novicida-containing phagosome in quiescent human macrophages and its maturation into a phagolysosome upon activation by IFN-gamma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.