Article
Polygenic risk scores for smoking: predictors for alcohol and cannabis use?
Addiction (Abingdon, England) - 1 Jul 2014
Vink Jacqueline M, Hottenga Jouke Jan, de Geus Eco J C, Willemsen Gonneke, Neale Michael C, Furberg Helena, Boomsma Dorret I
Abstract excerpt
BACKGROUND AND AIMS: A strong correlation exists between smoking and the use of alcohol and cannabis. This paper uses polygenic risk scores to explore the possibility of overlapping genetic factors. Those scores reflect a combined effect of selected risk alleles for smoking. METHODS: Summary-level P-values were available for smoking initiation, age at onset of smoking, cigarettes per day and smoking cessation...
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