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Article

The Promise of Polygenic Risk Prediction in Smoking Cessation: Evidence From Two Treatment Trials

14 Feb 2022

Abstract excerpt

INTRODUCTION: Tobacco use disorder is a complex behavior with a strong genetic component. Genome-wide association studies (GWAS) on smoking behaviors allow for the creation of polygenic risk scores (PRSs) to approximate genetic vulnerability. However, the utility of smoking-related PRSs in predicting smoking cessation in clinical trials remains unknown. AIMS AND METHODS: We evaluated the association between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35170738
DOI: 10.1093/ntr/ntac043

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