Article
The genetic aetiology of cannabis use initiation: a meta-analysis of genome-wide association studies and a SNP-based heritability estimation.
Addiction biology - 1 Sept 2013
Verweij Karin J H, Vinkhuyzen Anna A E, Benyamin Beben, Lynskey Michael T, Quaye Lydia, Agrawal Arpana, Gordon Scott D, Montgomery Grant W, Madden Pamela A F, Heath Andrew C, Spector Timothy D, Martin Nicholas G, Medland Sarah E
Abstract excerpt
While initiation of cannabis use is around 40% heritable, not much is known about the underlying genetic aetiology. Here, we meta-analysed two genome-wide association studies of initiation of cannabis use with > 10 000 individuals. None of the genetic variants reached genome-wide significance. We...
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