Article
Paternally induced transgenerational inheritance of susceptibility to diabetes in mammals.
Proceedings of the National Academy of Sciences of the United States of America - 4 Feb 2014
Wei Yanchang, Yang Cai-Rong, Wei Yan-Ping, Zhao Zhen-Ao, Hou Yi, Schatten Heide, Sun Qing-Yuan
Abstract excerpt
The global prevalence of prediabetes and type 2 diabetes (T2D) is increasing, and it is contributing to the susceptibility to diabetes and its related epidemic in offspring. Although the impacts of paternal impaired fasting blood glucose and glucose intolerance on the metabolism of offspring have been well established, the exact molecular and mechanistic basis that mediates these impacts remains largely unclear....
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