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Transgenerational epigenetic inheritance of diabetes risk as a consequence of early nutritional imbalances

17 Nov 2015

Abstract excerpt

In today's world, there is an unprecedented rise in the prevalence of chronic metabolic diseases, including obesity, insulin resistance and type 2 diabetes (T2D). The pathogenesis of T2D includes both genetic and environmental factors, such as excessive energy intake and physical inactivity. It has recently been suggested that environmental factors experienced during early stages of development, including the...

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PMID: 26573376
DOI: 10.1017/s0029665115004231

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