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Environmental epigenetic inheritance through gametes and implications for human reproduction

21 Nov 2014

Abstract excerpt

BACKGROUND: Traditional studies focused on DNA as the heritable information carrier that passes the phenotype from parents to offspring. However, increasing evidence suggests that information, that is independent of the DNA sequence, termed epigenetic information, can be inherited between generations. Recently, in our lab, we found that prediabetes in fathers increases the susceptibility to diabetes in offspring...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25416302
DOI: 10.1093/humupd/dmu061

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