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Article

Accuracy of imputation to infer unobserved APOE epsilon alleles in genome-wide genotyping data.

European journal of human genetics : EJHG - 1 Oct 2014

Radmanesh Farid, Devan William J, Anderson Christopher D, Rosand Jonathan, Falcone Guido J

Abstract excerpt

Apolipoprotein E, encoded by APOE, is the main apoprotein for catabolism of chylomicrons and very low density lipoprotein. Two common single-nucleotide polymorphisms (SNPs) in APOE, rs429358 and rs7412, determine the three epsilon alleles that are established genetic risk factors for late-onset Alzheimer's disease (AD), cerebral amyloid angiopathy, and intracerebral hemorrhage (ICH). These two SNPs are not...

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Identifiers

PMID: 24448547
DOI: 10.1038/ejhg.2013.308
PMCID: PMC4169533

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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