Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Concordance between direct and imputed APOE genotypes using 1000 Genomes data.

Journal of Alzheimer's disease : JAD - 1 Jan 2014

Oldmeadow Christopher, Holliday Elizabeth G, McEvoy Mark, Scott Rodney, Kwok John B J, Mather Karen, Sachdev Perminder, Schofield Peter, Attia John

Abstract excerpt

There are a growing number of large cohorts of older persons with genome-wide genotyping data available, but APOE is not included in any of the common microarray platforms. We compared directly measured APOE genotypes with those imputed using microarray data and the "1000 Genomes" dataset in a sample of 320 Caucasians. We find 90% agreement for ε2/ε3/ε4 genotypes and 93% agreement for predicting ε4 status,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoproteins E

Share to APOE gene

Share to Genetic Predisposition to Disease

Share to Genome

Share to Genotype

Source

Identifiers

PMID: 24903779
DOI: 10.3233/JAD-140846

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Concordance between direct and imputed APOE genotypes using 1000 Genomes data.PMID 24903779Read ↗

Accuracy of Inferred APOE Genotypes for a Range of Genotyping Arrays and Imputation Reference Panels.Semantic proximity Read ↗

Response to Comment on "ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank" by Kuo et al.Semantic proximity Read ↗

Identification of epigenome-wide DNA methylation differences between carriers of <i>APOE</i> ε4 and <i>APOE</i> ε2Semantic proximity Read ↗

Accuracy of Imputation for Apolipoprotein E ε Alleles in Genome-Wide Genotyping Data.Semantic proximity Read ↗

Identification of epigenome-wide DNA methylation differences between carriers of APOE ε4 and APOE ε2 alleles.Semantic proximity Read ↗

Phenome-Wide Association of<i>APOE</i>Alleles in the<i>All of Us</i>Research ProgramSemantic proximity Read ↗

ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank.Semantic proximity Read ↗

APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort.Semantic proximity Read ↗

Comment on "ApoE e4e4 Genotype and Mortality With COVID-19 in UK Biobank" by Kuo et al.Semantic proximity Read ↗

Commentary: APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort.Semantic proximity Read ↗

Phenome-wide association of APOE alleles in the All of Us Research ProgramSemantic proximity Read ↗

APOE Genotype and Statin Response: Evidence from the UK Biobank Baseline Assessment and Linked Mortality DataSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.