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Article

Role of mTOR signaling in the regulation of high glucose‑induced podocyte injury

4 Feb 2019

Abstract excerpt

Podocyte injury, which promotes progressive nephropathy, is considered a key factor in the progression of diabetic nephropathy. The mammalian target of rapamycin (mTOR) signaling cascade controls cell growth, survival and metabolism. The present study investigated the role of mTOR signaling in regulating high glucose (HG)-induced podocyte injury. MTT assay and flow cytometry assay results indicated that HG...

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PMID: 30906437
DOI: 10.3892/etm.2019.7236

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