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Article

A reduction in Ptprq associated with specific features of the deafness phenotype of the miR-96 mutant mouse diminuendo.

The European journal of neuroscience - 1 Mar 2014

Chen Jing, Johnson Stuart L, Lewis Morag A, Hilton Jennifer M, Huma Andreea, Marcotti Walter, Steel Karen P

Abstract excerpt

miR-96 is a microRNA, a non-coding RNA gene which regulates a wide array of downstream genes. The miR-96 mouse mutant diminuendo exhibits deafness and arrested hair cell functional and morphological differentiation. We have previously shown that several genes are markedly downregulated in the diminuendo organ of Corti; one of these is Ptprq, a gene known to be important for maturation and maintenance of hair...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24446963
DOI: 10.1111/ejn.12484
PMCID: PMC4065360

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