Article

Hearing impairment due to <i>Mir183/96/182</i> mutations suggests both loss and gain of function effects

2019-03-16

Abstract excerpt

The microRNA miR-96 is important for hearing, as point mutations in humans and mice result in dominant progressive hearing loss. Mir96 is expressed in sensory cells along with Mir182 and Mir183 , but the roles of these closely-linked microRNAs are as yet unknown. Here we analyse mice carrying null alleles of Mir182 , and of Mir183 and Mir96 together to investigate their roles in hearing. We found that Mir18...

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Literature Corpus work: 9c10e598-cf24-5de4-ba8a-7e305ec45846
DOI: 10.1101/579003

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