Article
A robust method for genome-wide association meta-analysis with the application to circulating insulin-like growth factor I concentrations.
Genetic epidemiology - 1 Feb 2014
Wang Tao, Zhou Baiyu, Guo Tingwei, Bidlingmaier Martin, Wallaschofski Henri, Teumer Alexander, Vasan Ramachandran S, Kaplan Robert C
Abstract excerpt
Genome-wide association studies (GWAS) offer an excellent opportunity to identify the genetic variants underlying complex human diseases. Successful utilization of this approach requires a large sample size to identify single nucleotide polymorphisms (SNPs) with subtle effects. Meta-analysis is a cost-efficient means to achieve large sample size by combining data from multiple independent GWAS; however, results...
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