Article
Heritability and coefficient of genetic variation analyses of phenotypic traits provide strong basis for high-resolution QTL mapping in the Collaborative Cross mouse genetic reference population.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2014
Iraqi Fuad A, Athamni Hanifa, Dorman Alexandra, Salymah Yasser, Tomlinson Ian, Nashif Aysar, Shusterman Ariel, Weiss Ervin, Houri-Haddad Yael, Mott Richard, Soller Morris
Abstract excerpt
Most biological traits of human importance are complex in nature; their manifestation controlled by the cumulative effect of many genetic factors interacting with one another and with the individual's life history. Because of this, mouse genetic reference populations (GRPs) consisting of collections of inbred lines or recombinant inbred lines (RIL) derived from crosses between inbred lines are of particular value...
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