Article
Altered lipid composition in Streptococcus pneumoniae cpoA mutants.
BMC microbiology - 20 Jan 2014
Meiers Marina, Volz Carsten, Eisel Jessica, Maurer Patrick, Henrich Bernhard, Hakenbeck Regine
Abstract excerpt
BACKGROUND: Penicillin-resistance in Streptococcus pneumoniae is mainly due to alterations in genes encoding the target enzymes for beta-lactams, the penicillin-binding proteins (PBPs). However, non-PBP genes are altered in beta-lactam-resistant laboratory mutants and confer decreased susceptibility to beta-lactam antibiotics. Two piperacillin resistant laboratory mutants of Streptococcus pneumoniae R6 contain...
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