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Article

The role of galacturonic acid in outer membrane stability in Klebsiella pneumoniae.

The Journal of biological chemistry - 29 Jul 2005

Frirdich Emilisa, Bouwman Catrien, Vinogradov Evgeny, Whitfield Chris

Abstract excerpt

In most members of the Enterobacteriaceae, including Escherichia coli and Salmonella, the lipopolysaccharide core oligosaccharide backbone is modified by phosphoryl groups. The negative charges provided by these residues are important in maintaining the barrier function of the outer membrane. Mutants lacking the core heptose region and the phosphate residues display pleiotrophic defects collectively known as the...

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Identifiers

PMID: 15929980
DOI: 10.1074/jbc.M504987200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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