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Article

Network signatures of nuclear and cytoplasmic density alterations in a model of pre and postmetastatic colorectal cancer.

Journal of biomedical optics - 1 Jan 2014

Damania Dhwanil, Subramanian Hariharan, Backman Vadim, Anderson Eric C, Wong Melissa H, McCarty Owen J T, Phillips Kevin G

Abstract excerpt

Cells contributing to the pathogenesis of cancer possess cytoplasmic and nuclear structural alterations that accompany their aberrant genetic, epigenetic, and molecular perturbations. Although it is known that architectural changes in primary and metastatic tumor cells can be quantified through variations in cellular density at the nanometer and micrometer spatial scales, the interdependent relationships among...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24441943
DOI: 10.1117/1.JBO.19.1.016016
PMCID: PMC4019418

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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