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Article

Nanoscale cellular changes in field carcinogenesis detected by partial wave spectroscopy.

Cancer research - 1 Jul 2009

Subramanian Hariharan, Roy Hemant K, Pradhan Prabhakar, Goldberg Michael J, Muldoon Joseph, Brand Randall E, Sturgis Charles, Hensing Thomas, Ray Daniel, Bogojevic Andrej, Mohammed Jameel, Chang Jeen-Soo, Backman Vadim

Abstract excerpt

Understanding alteration of cell morphology in disease has been hampered by the diffraction-limited resolution of optical microscopy (>200 nm). We recently developed an optical microscopy technique, partial wave spectroscopy (PWS), which is capable of quantifying statistical properties of cell structure at the nanoscale. Here we use PWS to show for the first time the increase in the disorder strength of the...

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Identifiers

PMID: 19549915
DOI: 10.1158/0008-5472.CAN-08-3895
PMCID: PMC2802178

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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