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Article

A Multimodal Imaging Framework to Advance Phenotyping of Living Label-free Breast Cancer Cells.

Journal of visualized experiments : JoVE - 22 Aug 2025

Bianchi Leonardo, Bresci Arianna, Kobayashi-Kirschvink Koseki J, Paroni Gabriela, Saccomandi Paola, So Peter T C, Kang Jeon Woong

Abstract excerpt

We present multimodal confocal Raman micro-spectroscopy (RS) and tomographic phase microscopy (TPM) for quick morpho-chemical phenotyping of human breast cancer cells (MDA-MB-231). Leveraging the non-perturbative nature of these advanced microscopy techniques, we captured detailed morpho-molecular data from living, label-free cells in their native physiological environment. Human bias-free data processing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 40920637
DOI: 10.3791/68498

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MB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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