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Article

Association of functional FEN1 genetic variants and haplotypes and breast cancer risk.

Gene - 15 Mar 2014

Lv Zheng, Liu Weilin, Li Dongmei, Liu Lisheng, Wei Jinyu, Zhang Jingfeng, Ge Yunxia, Wang Zhiqiong, Chen Hongwei, Zhou Changchun, Yuan Qipeng, Zhou Liqing, Yang Ming

Abstract excerpt

AIM: As a tumor suppressor, FEN1 plays an essential role in preventing tumorigenesis. Two functional germline variants (-69G>A and 4150G>T) in the FEN1 gene have been associated with DNA damage levels in coke-oven workers and multiple cancer risk in general populations. However, it is still unknown how these genetic variants are involved in breast cancer susceptibility. METHODS: We investigated the association...

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Identifiers

PMID: 24440783
DOI: 10.1016/j.gene.2014.01.025

Genes

FEN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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