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Article

Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk.

Human mutation - 1 Sept 2009

Yang Ming, Guo Huan, Wu Chen, He Yuefeng, Yu Dianke, Zhou Li, Wang Fang, Xu Jian, Tan Wen, Wang Guanghai, Shen Binghui, Yuan Jing, Wu Tangchun, Lin Dongxin

Abstract excerpt

Flap endonuclease 1 (FEN1) is a key enzyme in maintaining genomic stability and protecting against carcinogenesis. This study investigated whether functional variations in FEN1 gene are associated with DNA damage and lung cancer risk. Thirty DNA samples were sequenced to identify variants and fun...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19618370
DOI: 10.1002/humu.21060

Genes

FEN1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19618370-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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