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Article

A FRET-based approach for quantitative evaluation of forskolin-induced pendrin trafficking at the plasma membrane in bronchial NCI H292 cells.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2013

Tamma Grazia, Ranieri Marianna, Dossena Silvia, Di Mise Annarita, Nofziger Charity, Svelto Maria, Paulmichl Markus, Valenti Giovanna

Abstract excerpt

BACKGROUND: Human pendrin (SLC26A4, PDS) is an integral membrane protein acting as an electroneutral anion exchanger. Loss of function mutations in pendrin protein cause Pendred syndrome, a disorder characterized by sensorineural deafness and a partial iodide organification defect that may lead to thyroid goiter. Additionally, pendrin up-regulation could play a role in the pathogenesis of several diseases...

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PMID: 24429826
DOI: 10.1159/000356639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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A FRET-based approach for quantitative evaluation of forskolin-induced pendrin trafficking at the plasma membrane in bronchial NCI H292 cells.PMID 24429826Read ↗

[Pendrin: physiology, molecular biology and clinical importance].Semantic proximity Read ↗

Analysis of cellular localization and function of carboxy-terminal mutants of pendrin.Semantic proximity Read ↗

Genetics and phenomics of Pendred syndrome.Semantic proximity Read ↗

Mutations of the PDS Gene, Encoding Pendrin, Are Associated with Protein Mislocalization and Loss of Iodide Efflux: Implications for Thyroid Dysfunction in Pendred SyndromeSemantic proximity Read ↗

Mutations of the PDS gene, encoding pendrin, are associated with protein mislocalization and loss of iodide efflux: implications for thyroid dysfunction in Pendred syndrome.Semantic proximity Read ↗

Functional characterization of wild-type and a mutated form of SLC26A4 identified in a patient with Pendred syndrome.Semantic proximity Read ↗

Clinical and molecular characteristics of Pendred syndrome.Semantic proximity Read ↗

Asymmetric Pendrin Homodimer Reveals its Molecular Mechanism as Anion ExchangerSemantic proximity Read ↗

Identification of allelic variants of pendrin (SLC26A4) with loss and gain of function.Semantic proximity Read ↗

Pendrin function and regulation in Xenopus oocytes.Semantic proximity Read ↗

Functional characterization of pendrin in a polarized cell system. Evidence for pendrin-mediated apical iodide efflux.Semantic proximity Read ↗

Asymmetric Pendrin Homodimer Reveals its Molecular Mechanism as Anion ExchangerSemantic proximity Read ↗

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