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Article

Pendrin function and regulation in Xenopus oocytes.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2011

Reimold Fabian R, Heneghan John F, Stewart Andrew K, Zelikovic Israel, Vandorpe David H, Shmukler Boris E, Alper Seth L

Abstract excerpt

SLC26A4/PDS mutations cause Pendred Syndrome and non-syndromic deafness. but some aspects of function and regulation of the SLC26A4 polypeptide gene product, pendrin, remain controversial or incompletely understood. We have therefore extended the functional analysis of wildtype and mutant pendrin in Xenopus oocytes, with studies of isotopic flux, electrophysiology, and protein localization. Pendrin mediated...

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Identifiers

PMID: 22116357
DOI: 10.1159/000335106
PMCID: PMC3709188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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