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Article

Clinical significance of the ubiquitin ligase UBE3C in hepatocellular carcinoma revealed by exome sequencing.

Hepatology (Baltimore, Md.) - 1 Jun 2014

Jiang Jia-Hao, Liu Yan-Feng, Ke Ai-Wu, Gu Fang-Ming, Yu Yao, Dai Zhi, Gao Qiang, Shi Guo-Ming, Liao Bo-Yi, Xie You-Hua, Fan Jia, Huang Xiao-Wu, Zhou Jian

Abstract excerpt

UNLABELLED: Virus-induced hepatocarcinogenesis involves a series of histological developmental processes with the stepwise acquisition of several genetic changes that are necessary for the malignant transformation of hepatocytes. Although genetic alterations are known to be involved in the pathogenesis of hepatocellular carcinoma (HCC), little is known about the contributions of specific genes to this process. To...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24425307
DOI: 10.1002/hep.27012

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