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Article

Mutations in VPS26A are not a frequent cause of Parkinson's disease.

Neurobiology of aging - 1 Jun 2014

Koschmidder Eva, Mollenhauer Brit, Kasten Meike, Klein Christine, Lohmann Katja

Abstract excerpt

VPS35 mutations have been identified as a cause of autosomal dominantly inherited Parkinson's disease (PD). VPS35 interacts with VPS26A in the retromer complex that links mitochondrial and lysosomal pathways, which have both been shown to be dysfunctional in PD. Thus, mutations in VPS26A may be associated with PD. To test this hypothesis, we screened 245 idiopathic PD patients and 185 control subjects for...

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Share to Aged, 80 and over
Share to Epistasis, Genetic
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24417787
DOI: 10.1016/j.neurobiolaging.2013.12.016

Genes

VPS35

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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