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Article

A genetic variant in the promoter region of miR-106b-25 cluster predict clinical outcome of HBV-related hepatocellular carcinoma in Chinese.

PloS one - 1 Jan 2014

Qi Fuzhen, Huang Mingde, Pan Yun, Liu Yao, Liu Jibin, Wen Juan, Xie Kaipeng, Shen Hongbing, Ma Hongxia, Miao Yi, Hu Zhibin

Abstract excerpt

BACKGROUND: MiR-106b-25 cluster, hosted in intron 13 of MCM7, may play integral roles in diverse processes including immune response, tumorigenesis and progression. A single nucleotide polymorphism (SNP), rs999885, is located in the promoter region of MCM7. Our previous study showed that the A to G base change of rs999885 may provide an increased risk for HCC in HBV persistent carriers by altering the expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24416400
DOI: 10.1371/journal.pone.0085394
PMCID: PMC3885710

Genes

MCM7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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