Article
Von Hippel-Lindau gene single nucleotide polymorphism (rs1642742) may be related to the occurrence and metastasis of HBV-related hepatocellular carcinoma.
Medicine - 3 Sept 2021
Chen Xuebing, Zhang Hao, Ou Shimei, Chen Huijuan
Abstract excerpt
ABSTRACT: It is well-known that microRNAs are able to regulate the expression of target mRNAs through complementary base-pairing to their 3'-untranslated regions (3'UTR) sequences. This study aimed to investigate whether single nucleotide polymorphisms resided in the 3'UTR sequences in patients with chronic hepatitis B viruses (HBV) infection are associated with the development and metastasis of hepatocellular...
Topics
- Adult
- Carcinoma, Hepatocellular
- Female
- Hepatitis B, Chronic
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Neoplasm Metastasis
- Polymorphism, Single Nucleotide
- Von Hippel-Lindau Tumor Suppressor Protein
