Article
Characterisation of a natural variant of the γ-butyrolactone signalling receptor.
BMC research notes - 27 Jul 2012
Gottelt Marco, Hesketh Andrew, Bunet Robert, Puri Pranav, Takano Eriko
Abstract excerpt
BACKGROUND: The control of antibiotic production in Streptomyces coelicolor A3(2) involves complicated regulatory networks with multiple regulators controlling the expression of antibiotic biosynthetic pathways. One such regulatory network is that of the γ-butyrolactones, the so-called S. coelicolor butanolide (SCB) system. The γ-butyrolactones in this system serve as signalling molecules and bind to the receptor...
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