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Article

Maximum likelihood inference of the evolutionary history of a PPI network from the duplication history of its proteins.

IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000

Li Si, Choi Kwok Pui, Wu Taoyang, Zhang Louxin

Abstract excerpt

Evolutionary history of protein-protein interaction (PPI) networks provides valuable insight into molecular mechanisms of network growth. In this paper, we study how to infer the evolutionary history of a PPI network from its protein duplication relationship. We show that for a plausible evolutionary history of a PPI network, its relative quality, measured by the so-called loss number, is independent of the...

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Identifiers

PMID: 24407300
DOI: 10.1109/TCBB.2013.14

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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