Article
The evolutionary dynamics of protein-protein interaction networks inferred from the reconstruction of ancient networks.
PloS one - 1 Jan 2013
Jin Yuliang, Turaev Dmitrij, Weinmaier Thomas, Rattei Thomas, Makse Hernán A
Abstract excerpt
Cellular functions are based on the complex interplay of proteins, therefore the structure and dynamics of these protein-protein interaction (PPI) networks are the key to the functional understanding of cells. In the last years, large-scale PPI networks of several model organisms were investigated. A number of theoretical models have been developed to explain both the network formation and the current structure....
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