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Article

Late cortical plasticity in motor and auditory cortex: role of met-allele in BDNF Val66Met polymorphism.

The international journal of neuropsychopharmacology - 1 May 2014

Teo James T H, Bentley Graham, Lawrence Philip, Soltesz Fruzsina, Miller Sam, Willé David, McHugh Simon, Dodds Chris, Lu Bai, Croft Rodney J, Bullmore Edward T, Nathan Pradeep J

Abstract excerpt

The brain-derived neurotropic factor (BDNF) Val66Met polymorphism has been associated with abnormalities of synaptic plasticity in animal models, and abnormalities in motor cortical plasticity have also been described in humans using transcranial direct current stimulation. No study has yet been done on plasticity in non-motor regions, and the effect of two Met alleles (i.e. 'Met dose') is not well understood. We...

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Source

Identifiers

PMID: 24405657
DOI: 10.1017/S1461145713001636

Genes

BDNF

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