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Article

A common polymorphism in the brain-derived neurotrophic factor gene (BDNF) modulates human cortical plasticity and the response to rTMS.

The Journal of physiology - 1 Dec 2008

Cheeran Binith, Talelli Penelope, Mori Francesco, Koch Giacomo, Suppa Antonio, Edwards Mark, Houlden Henry, Bhatia Kailash, Greenwood Richard, Rothwell John C

Abstract excerpt

The brain-derived neurotrophic factor gene (BDNF) is one of many genes thought to influence synaptic plasticity in the adult brain and shows a common single nucleotide polymorphism (BDNF Val66Met) in the normal population that is associated with differences in hippocampal volume and episodic memory. It is also thought to influence possible synaptic changes in motor cortex following a simple motor learning task....

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Source

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Identifiers

PMID: 18845611
DOI: 10.1113/jphysiol.2008.159905
PMCID: PMC2655403

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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