Article
A preliminary analysis of gene pleiotropy estimated from protein sequences.
Journal of experimental zoology. Part B, Molecular and developmental evolution - 15 Mar 2010
Su Zhixi, Zeng Yanwu, Gu Xun
Abstract excerpt
Biologists have long recognized the importance of gene pleiotropy, that is, single genes affect multiple traits, which is one of the most commonly observed attributes of genes. Yet the extent of gene pleiotropy has been seriously under-explored. Theoretically, Fisher's model assumed a universal pleiotropy, that is, a mutation can potentially affect all phenotypic traits. On the other hand, experimental assays of...
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