A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility.

doi:10.1186/ar4432

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Article

A genome-wide association study follow-up suggests a possible role for PPARG in systemic sclerosis susceptibility.

Arthritis research & therapy - 9 Jan 2014

López-Isac Elena, Bossini-Castillo Lara, Simeon Carmen P, Egurbide María Victoria, Alegre-Sancho Juan José, Callejas Jose Luis, Roman-Ivorra José Andrés, Freire Mayka, Beretta Lorenzo, Santaniello Alessandro, Airó Paolo, Lunardi Claudio, Hunzelmann Nicolas, Riemekasten Gabriela, Witte Torsten, Kreuter Alexander, Distler Jörg H W, Schuerwegh Annemie J, Vonk Madelon C, Voskuyl Alexandre E, Shiels Paul G, van Laar Jacob M, Fonseca Carmen, Denton Christopher, Herrick Ariane, Worthington Jane, Assassi Shervin, Koeleman Bobby P, Mayes Maureen D, Radstake Timothy R D J, Martin Javier

Abstract excerpt

INTRODUCTION: A recent genome-wide association study (GWAS) comprising a French cohort of systemic sclerosis (SSc) reported several non-HLA single-nucleotide polymorphisms (SNPs) showing a nominal association in the discovery phase. We aimed to identify previously overlooked susceptibility varian...

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Identifiers

PMID: 24401602
DOI: 10.1186/ar4432
PMCID: PMC3978735

Genes

PPARG
CHRNA9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24401602-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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