Article
Association between a CTGF gene polymorphism and systemic sclerosis in a French population.
The Journal of rheumatology - 1 Feb 2010
Granel Brigitte, Argiro Laurent, Hachulla Eric, Fajardy Isabelle, Weiller Pierre-Jean, Durand Jean-Marc, Frances Yves, Dombey Anne-Marie, Marquet Sandrine, Lesavre Nathalie, Disdier Patrick, Bernard Fanny, Hatron Pierre-Yves, Chevillard Christophe
Abstract excerpt
OBJECTIVE: Systemic sclerosis (SSc) is a life-threatening autoimmune disease characterized by chronic fibrosis of the skin and internal organs. Connective tissue growth factor (CTGF) is believed to be a primary mediator of chronic fibrosis. We assessed the possible association between 7 single-nu...
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