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Article

A polymorphism at IGF1 locus is associated with carotid intima media thickness and endothelium-dependent vasodilatation.

Atherosclerosis - 1 Jan 2014

Sesti Giorgio, Mannino Gaia Chiara, Andreozzi Francesco, Greco Annalisa, Perticone Maria, Sciacqua Angela, Marini Maria A, Perticone Francesco

Abstract excerpt

OBJECTIVE: Whether IGF-1 has a protective or a detrimental role in vascular homeostasis remains unsettled. There is evidence that the C/T polymorphism rs35767 near the promoter region of the IGF1 gene located in chromosome 12 is associated with plasma IGF-1 levels. We investigated the effects of...

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Source

Identifiers

PMID: 24401213
DOI: 10.1016/j.atherosclerosis.2013.10.024

Genes

IGF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24401213-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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