Article
Estrogen receptor 2 polymorphism and carotid intima-media thickness.
Genetic testing - 1 Dec 2008
Nikkari Seppo T, Henttonen Antti, Kunnas Tarja, Kähönen Mika, Hutri-Kähönen Nina, Juonala Markus, Marniemi Jukka, Viikari Jorma, Raitakari Olli T, Lehtimäki Terho
Abstract excerpt
AIMS: The present study was designed to investigate the effects of estrogen receptor 2 gene (ESR2) rs1256049 polymorphism to carotid artery intima-media thickness (CIMT), as part of the Cardiovascular Risk in Young Finns Study. RESULTS: The frequencies of ESR2 genotypes G/G, G/A, and A/A were 85.1%, 14.3%, and 0.7%, respectively, in the whole study population (n = 2211). Compared with subjects with genotype GG,...
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