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Article

Atheroprotective Properties of Serum IGF-1 in the Carotid and Coronary Territories and Beneficial Role on the Physical Fitness of the Oldest Old.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Oct 2016

Córdova Claudio, Boullosa Daniel A, Custódio Misael R M, Quaglia Luiz A, Santos Simone N, Freitas Wladimir M, Sposito Andrei C, Nóbrega Otávio T

Abstract excerpt

Our aim was to investigate whether physiological levels of soluble insulin-like growth factor-1 (IGF-1) associate with coronary and carotid atherosclerotic burden and physical fitness in the oldest old by means of a cross-sectional study including 100 community-dwelling individuals with no previous cardiovascular events. Linear correlation was found between IGF-1 and intima-media thickness, number of carotid...

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PMID: 26714565
DOI: 10.1093/gerona/glv216

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