Article
RANK-mediated signaling network and cancer metastasis.
Cancer metastasis reviews - 1 Sept 2014
Chu Gina Chia-Yi, Chung Leland W K
Abstract excerpt
Cancer metastasis is highly inefficient and complex. Common features of metastatic cancer cells have been observed using cancer cell lines and genetically reconstituted mouse and human tumor xenograft models. These include cancer cell interaction with the tumor microenvironment and the ability of cancer cells to sense extracellular stimuli and adapt to adverse growth conditions. This review summarizes the...
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