Article
Epithelial-mesenchymal-transition regulators in prostate cancer: Androgens and beyond.
The Journal of steroid biochemistry and molecular biology - 1 Feb 2017
Nakazawa Mary, Kyprianou Natasha
Abstract excerpt
Castration resistant prostate cancer (CRPC) remains one of the leading causes of cancer deaths among men. Conventional therapies targeting androgen signaling driven tumor growth have provided limited survival benefit in patients. Recent identification of the critical molecular and cellular events surrounding tumor progression, invasion, and metastasis to the bone as well as other sites provide new insights in...
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