Article

RANKL Immunisation Inhibits Prostate Cancer Metastasis by Modulating EMT Through A RANKL-Dependent Pathway

2020-11-17

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Prostate cancer (PCa) morbidity in the majority of patients is due to metastatic events, which are a clinical obstacle. Therefore, a better understanding of the mechanism underlying metastasis is imperative if we are to develop novel therapeutic strategies. Receptor activator of nuclear factor kappa-B (NF-κB) ligand (RANKL) regulates bone remodelling. RANKL was...

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Literature Corpus work: 1615852f-3a50-5f93-8fea-42bf7a997613
DOI: 10.21203/rs.3.rs-105442/v1

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