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Article

Autoregulation of lin-4 microRNA transcription by RNA activation (RNAa) in C. elegans.

Cell cycle (Georgetown, Tex.) - 1 Jan 2014

Turner Michael J, Jiao Alan L, Slack Frank J

Abstract excerpt

The conserved lin-4 microRNA (miRNA) regulates the proper timing of stem cell fate decisions in C. elegans by regulating stemness genes such as lin-14 and lin-28. (1)(-) (3) While lin-4 is upregulated toward the end of the first larval stage and functions as an essential developmental timing "switch", little is known about how lin-4 expression is regulated. (4) Here we show that in C. elegans hypodermal seam...

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Identifiers

PMID: 24398561
DOI: 10.4161/cc.27679
PMCID: PMC3979913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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