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Article

Modularity and predictability in cell signaling and decision making.

Molecular biology of the cell - 5 Nov 2014

Atay Oguzhan, Skotheim Jan M

Abstract excerpt

Cells make decisions to differentiate, divide, or apoptose based on multiple signals of internal and external origin. These decisions are discrete outputs from dynamic networks comprised of signaling pathways. Yet the validity of this decomposition of regulatory proteins into distinct pathways is unclear because many regulatory proteins are pleiotropic and interact through cross-talk with components of other...

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Identifiers

PMID: 25368418
DOI: 10.1091/mbc.E14-02-0718
PMCID: PMC4230600

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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