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Article

Highly conserved influenza A sequences as T cell epitopes-based vaccine targets to address the viral variability.

Human vaccines - 1 Apr 2011

Tan Paul Thiamjoo, Khan Asif M, August J Thomas

Abstract excerpt

Vaccines are the only proven effective method for prevention of human infectious diseases. Almost all traditional vaccines require activating immunological memory B cells to secrete neutralizing antibodies against invading pathogens. The complication with influenza viruses is the high viral mutation rate that results in immune escape through modification of the B cell epitopes. Studies of T-cell immunity to...

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Identifiers

PMID: 21471731
DOI: 10.4161/hv.7.4.13845

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