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Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals

18 Sept 2008

Abstract excerpt

The threat of avian influenza A (H5N1) infection in humans remains a global health concern. Current influenza vaccines stimulate antibody responses against the surface glycoproteins but are ineffective against strains that have undergone significant antigenic variation. An alternative approach is to stimulate pre-existing memory T cells established by seasonal human influenza A infection that could cross-react...

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PMID: 18802496
DOI: 10.1172/jci32460

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