Human Cytotoxic T-Lymphocyte Repertoire to Influenza A Viruses

doi:10.1128/jvi.72.11.8682-8689.1998

Article

Human Cytotoxic T-Lymphocyte Repertoire to Influenza A Viruses

1 Nov 1998

Abstract excerpt

The murine CD8(+) cytotoxic-T-lymphocyte (CTL) repertoire appears to be quite limited in response to influenza A viruses. The CTL responses to influenza A virus in humans were examined to determine if the CTL repertoire is also very limited. Bulk cultures revealed that a number of virus proteins were recognized in CTL assays. CTL lines were isolated from three donors for detailed study and found to be specific...

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