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Article

Genetic variants associated with Sjögren's disease subtypes stratified by clinical feature.

Frontiers in immunology - 1 Jan 2026

Enduru Nitesh, Iwaya Chihiro, Suzuki Akiko, Zhao Zhongming, Iwata Junichi

Abstract excerpt

Introduction: Sjögren's disease (SjD) is a chronic autoimmune disorder characterized by dry mouth (xerostomia) and dry eyes (xerophthalmia) due to inflammation in exocrine glands, particularly the salivary and lacrimal glands. The condition presents a wide variety of clinical features, suggesting that it may involve heterogeneous conditions without a clear boundary. Although genome-wide association studies (GWAS)...

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Identifiers

PMID: 42158869
DOI: 10.3389/fimmu.2026.1766685
PMCID: PMC13180836

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SSB

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