Article
Important functional roles of basigin in thymocyte development and T cell activation.
International journal of biological sciences - 1 Jan 2013
Yao Hui, Teng Yan, Sun Qian, Xu Jing, Chen Ya-Tong, Hou Ning, Cheng Xuan, Yang Xiao, Chen Zhi-Nan
Abstract excerpt
Basigin is a highly glycosylated transmembrane protein that is expressed in a broad range of tissues and is involved in a number of physiological and pathological processes. However, the in vivo role of basigin remains unknown. To better understand the physiological and pathological functions of basigin in vivo, we generated a conditional null allele by introducing two loxP sites flanking exons 2 and 7 of the...
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